Thom Yorke hosted a guest show on 21 June 2023. Thom Yorke has been played on NTS over 110 times, featured on 103 episodes and was first played on 30 November 2012.

Thomas Edward Yorke is an English musician who is the main vocalist and songwriter of the rock band Radiohead. A multi-instrumentalist, he mainly plays guitar and keyboards and is noted for his falsetto. He has been described by Rolling Stone as one of the greatest and most influential singers of his generation.

Yorke formed Radiohead with schoolmates at Abingdon School in Oxfordshire. Their 1992 debut single, "Creep", made Yorke a celebrity, and Radiohead went on to achieve critical acclaim and sales of over 30 million albums. Yorke's early influences included alternative rock acts such as Pixies and R.E.M. With Radiohead's fourth album, Kid A, Yorke moved into electronic music, influenced by Warp acts such as Aphex Twin. With the artist Stanley Donwood, Yorke creates artwork for Radiohead albums and his other projects. He often incorporates "erratic" dancing into his performances.

Yorke's solo work comprises mainly electronic music. His debut solo album, The Eraser, was released in 2006. To perform it live, in 2009, he formed a new band, Atoms for Peace, with musicians including the Red Hot Chili Peppers bassist Flea and the Radiohead producer Nigel Godrich. They released an album, [album artist=Atoms for Peace Amok[/album], in 2013. Yorke's second solo album, Tomorrow's Modern Boxes, was released in 2014, followed by Anima in 2019. In 2021, Yorke debuted a new band, the Smile, with the Radiohead guitarist Jonny Greenwood and the jazz drummer Tom Skinner. Yorke has collaborated with artists including PJ Harvey, Björk, Flying Lotus and Modeselektor, and has composed for film and theatre. His first feature film soundtrack, Suspiria, was released in October 2018.

Yorke is an activist on behalf of human rights, animal rights, environmental and anti-war causes, and his lyrics incorporate political themes. He has been critical of the music industry, particularly of major labels and streaming services such as Spotify. With Radiohead and his solo work, he has employed alternative release platforms such as pay-what-you-want and BitTorrent. He was inducted into the Rock and Roll Hall of Fame as a member of Radiohead in 2019.