On 22 October 2023, Matmos was a guest on 75 Years of Folkways Records; on 19 October 2016 was a guest on Unsound 2016; and on 9 May 2015 was a guest on SKYAPNEA. Matmos has been played on NTS over 70 times, featured on 73 episodes and was first played on 22 December 2013.

Matmos is an experimental electronic music duo originally from San Francisco but now residing in Baltimore. M. C. (Martin) Schmidt and Drew Daniel are the core members, but they frequently include other artists on their records and in their performances, including notably J Lesser. Apart from releasing seven full-length studio albums and numerous collaborative works, Matmos is also well known for their collaboration with Icelandic singer and musician Björk, both on studio recordings and live tours. After being signed to Matador Records for nine years, Matmos signed with Thrill Jockey in 2012. The name Matmos refers to the seething lake of evil slime beneath the city Sogo in the 1968 film Barbarella.

In 1998, Matmos remixed the Björk single Alarm Call. Subsequently, Matmos worked with Björk on her albums Vespertine (2001) and Medúlla (2004), as well as her Vespertine and Greatest Hits tours. In November 2004, Matmos spent 97 hours in the Yerba Buena Center for the Arts as artists in residence, performing music with friends, musical guests and onlookers. The live album Work, Work, Work, essentially a "best of" collection of the session, was released as a free download from their website.

Matmos gained notoriety for their use of samples including "freshly cut hair" and "the amplified neural activity of crayfish" on their first album and "recorded the snips, clicks, snaps, and squelches of various surgical procedures, then nipped and tucked them into seven remarkably accessible, melodic pieces of experimental techno" for their album A Chance to Cut Is a Chance to Cure.

In 2011, Matmos participated in a programmed evening of events with the visual arts organisation Auto Italia South East. The event was produced in collaboration with record label Upset The Rhythm.co.uk/ Upset The Rhythm and included contributions from experimental electronic musicians Jon Wiese and Birds of Delay. Matmos have since collaborated with a large number of visual artists and arts organisations, including Cafe Oto and Metal.

M. C. Schmidt and Drew Daniel are also a couple, as stated in an interview in BUTT Magazine.

Schmidt formerly worked as a teacher in the New Genres Department at the San Francisco Art Institute.

Daniel successfully defended his dissertation on the literary cult of melancholy, directed by Janet Adelman at the University of California, Berkeley, and is currently an associate professor in the Department of English at Johns Hopkins University. This brought the band to relocate their home base to Baltimore in August 2007. Daniel also has a personal dance music project, The Soft Pink Truth. He is a contributing writer to the online music magazine Pitchfork Media, and wrote an essay about the Throbbing Gristle album 20 Jazz Funk Greats for the Continuum Books series 33 1/3. Both Schmidt and Daniel appeared in the Sagan music film Unseen Forces by Ryan Junell.